Join us for this month’s webinar with Dr. Sonam Tulsyan, who will present her work on investigating the complex genomic landscape of HPV-associated oropharyngeal squamous cell carcinoma (OPSCC). Persistent HPV infection is responsible for nearly 70% of OPSCC cases in the U.S., yet the molecular mechanisms driving tumor development remain poorly understood. To address this gap, Dr. Tulsyan applied long-read whole genome sequencing to analyze matched tumor and non-tumor biopsies, uncovering patterns of HPV integration and associated genomic alterations.
This webinar will cover:
The use of long-read sequencing to profile HPV+ OPSCC samples
Key findings on HPV integration events, structural variants, and methylation differences
Implications for understanding HPV subtype behavior and oncogenic potential
Don't miss this opportunity to explore how high-resolution sequencing is advancing our knowledge of HPV-driven cancers.
About the speaker
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Dr. Sonam Tulsyan
Dr. Sonam Tulsyan is a postdoctoral fellow in the Laboratory of Translational Genomics (LTG) at the National Cancer Institute’s Division of Cancer Epidemiology and Genetics (DCEG), where she has been working since June 2023. She earned her Ph.D. in biotechnology from Dr. A.P.J. Abdul Kalam Technical University in Lucknow, India. Under the mentorship of Dr. Michael Dean, her current research focuses on HPV-associated cancers, particularly using long-read sequencing to characterize viral types, integration patterns, and genomic alterations such as point mutations, structural variants, and differential methylation between tumor and normal tissues.